4KPH
Structure of the Fab fragment of N62, a protective monoclonal antibody to the nonreducing end of Francisella tularensis O-antigen
Summary for 4KPH
| Entry DOI | 10.2210/pdb4kph/pdb |
| Descriptor | N62 light chain, N62 heavy chain, ACETATE ION, ... (4 entities in total) |
| Functional Keywords | antibody, immunoglobulin, immune system, carbohydrate/sugar binding, plasma |
| Biological source | Mus musculus More |
| Total number of polymer chains | 4 |
| Total formula weight | 91882.55 |
| Authors | Lu, Z.,Rynkiewicz, M.J.,Yang, C.-Y.,Madico, G.,Perkins, H.M.,Wang, Q.,Costello, C.E.,Zaia, J.,Seaton, B.A.,Sharon, J. (deposition date: 2013-05-13, release date: 2013-07-24, Last modification date: 2023-09-20) |
| Primary citation | Lu, Z.,Rynkiewicz, M.J.,Yang, C.Y.,Madico, G.,Perkins, H.M.,Wang, Q.,Costello, C.E.,Zaia, J.,Seaton, B.A.,Sharon, J. The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology, 140:374-389, 2013 Cited by PubMed: 23844703DOI: 10.1111/imm.12150 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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