4KPH

Structure of the Fab fragment of N62, a protective monoclonal antibody to the nonreducing end of Francisella tularensis O-antigen

4KPH の概要

• エントリーDOI: 10.2210/pdb4kph/pdb
• 分子名称: N62 light chain, N62 heavy chain, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: antibody, immunoglobulin, immune system, carbohydrate/sugar binding, plasma
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 91882.55

構造登録者

Lu, Z.,Rynkiewicz, M.J.,Yang, C.-Y.,Madico, G.,Perkins, H.M.,Wang, Q.,Costello, C.E.,Zaia, J.,Seaton, B.A.,Sharon, J. (登録日: 2013-05-13, 公開日: 2013-07-24, 最終更新日: 2023-09-20)

• 主引用文献: Lu, Z.,Rynkiewicz, M.J.,Yang, C.Y.,Madico, G.,Perkins, H.M.,Wang, Q.,Costello, C.E.,Zaia, J.,Seaton, B.A.,Sharon, J.; The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.; Immunology, 140:374-389, 2013; PubMed: 23844703; DOI: 10.1111/imm.12150

実験手法

X-RAY DIFFRACTION (2.59 Å)