4KP0
Crystal Structure of the human Chymase with TJK002
Summary for 4KP0
| Entry DOI | 10.2210/pdb4kp0/pdb |
| Descriptor | Chymase, 4-({1-[(4-methyl-1-benzothiophen-3-yl)methyl]-1H-benzimidazol-2-yl}sulfanyl)butanoic acid (3 entities in total) |
| Functional Keywords | hydrolase, protease, serine protease, benzimidazole, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P23946 |
| Total number of polymer chains | 1 |
| Total formula weight | 25463.50 |
| Authors | Kakuda, S.,Takimoto-Kamimura, M. (deposition date: 2013-05-12, release date: 2013-10-30, Last modification date: 2023-11-08) |
| Primary citation | Matsumoto, Y.,Kakuda, S.,Koizumi, M.,Mizuno, T.,Muroga, Y.,Kawamura, T.,Takimoto-Kamimura, M. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor J.SYNCHROTRON RADIAT., 20:914-918, 2013 Cited by PubMed: 24121339DOI: 10.1107/S0909049513020748 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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