4KGZ

The R state structure of E. coli ATCase with UTP and Magnesium bound

Summary for 4KGZ

Entry DOI	10.2210/pdb4kgz/pdb
Related	4KGV 4KGX 4KH0 4KH1
Descriptor	Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... (7 entities in total)
Functional Keywords	pyrimidine nucleotide biosynthesis, feedback inhibition, competing pathway product activation, allostery, transferase
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	105587.69
Authors	Cockrell, G.M.,Zheng, Y.,Guo, W.,Peterson, A.W.,Kantrowitz, E.R. (deposition date: 2013-04-29, release date: 2013-11-27, Last modification date: 2023-09-20)
Primary citation	Cockrell, G.M.,Zheng, Y.,Guo, W.,Peterson, A.W.,Truong, J.K.,Kantrowitz, E.R. New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 52:8036-8047, 2013 Cited by PubMed: 24138583 DOI: 10.1021/bi401205n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation