4K75

CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)

4K75 の概要

• エントリーDOI: 10.2210/pdb4k75/pdb
• 関連するPDBエントリー: 4JOP 4JOR 4K6Y 4K72 4K76 4K78
• 分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide (3 entities in total)
• 機能のキーワード: pdz domain, cal, pist, fig, pdz-peptide complex, cftr associated ligand, cftr, peptide binding protein-protein binding complex, peptide binding protein/protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 10682.13

構造登録者

Amacher, J.F.,Madden, D.R. (登録日: 2013-04-16, 公開日: 2014-01-22, 最終更新日: 2023-09-20)

• 主引用文献: Amacher, J.F.,Cushing, P.R.,Brooks, L.,Boisguerin, P.,Madden, D.R.; Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.; Structure, 22:82-93, 2014; PubMed: 24210758; DOI: 10.1016/j.str.2013.09.019

実験手法

X-RAY DIFFRACTION (1.5 Å)