4K5C

From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display

Summary for 4K5C

Entry DOI	10.2210/pdb4k5c/pdb
Related	4K5A 4K5B
Descriptor	Loop Designed Ankyrin Repeat Protein Nran1_G06_C (2 entities in total)
Functional Keywords	structural protein
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	39622.36
Authors	Schilling, J.,Schoeppe, J.,Plueckthun, A. (deposition date: 2013-04-14, release date: 2013-11-13, Last modification date: 2024-03-20)
Primary citation	Schilling, J.,Schoeppe, J.,Plueckthun, A. From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display J.Mol.Biol., 426:691-721, 2014 Cited by PubMed: 24513107 DOI: 10.1016/j.jmb.2013.10.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation