4K2G
Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A33442372
Summary for 4K2G
Entry DOI | 10.2210/pdb4k2g/pdb |
Related | 3SRA 3SRB 3SRC 4K2F |
Descriptor | Acyl-homoserine lactone acylase PvdQ, 1,2-ETHANEDIOL, (2S)-(4-fluorophenyl)[6-(trifluoromethyl)pyridin-2-yl]ethanenitrile, ... (5 entities in total) |
Functional Keywords | amidohydrolase, bacterial protein, catalytic domain, high-throughput screening assays, molecular sequence data, oligopeptides, small molecule libraries, structure-activity relationship, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Pseudomonas aeruginosa More |
Cellular location | Periplasm (Probable): Q9I194 Q9I194 |
Total number of polymer chains | 2 |
Total formula weight | 80232.01 |
Authors | Drake, E.J.,Wurst, J.M.,Theriault, J.R.,Munoz, B.,Gulick, A.M. (deposition date: 2013-04-09, release date: 2014-06-18, Last modification date: 2023-09-20) |
Primary citation | Wurst, J.M.,Drake, E.J.,Theriault, J.R.,Jewett, I.T.,VerPlank, L.,Perez, J.R.,Dandapani, S.,Palmer, M.,Moskowitz, S.M.,Schreiber, S.L.,Munoz, B.,Gulick, A.M. Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine. Acs Chem.Biol., 9:1536-1544, 2014 Cited by PubMed: 24824984DOI: 10.1021/cb5001586 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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