4K2F

Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A08522488

4K2F の概要

• エントリーDOI: 10.2210/pdb4k2f/pdb
• 関連するPDBエントリー: 3SRA 3SRB 3SRC 4K2G
• 分子名称: Acyl-homoserine lactone acylase PvdQ, 1,2-ETHANEDIOL, (2S)-(4-chlorophenyl)(6-chloropyridin-2-yl)ethanenitrile, ... (5 entities in total)
• 機能のキーワード: amidohydrolase, bacterial protein, catalytic domain, high-throughput screening assays, molecular sequence data, oligopeptides, small molecule libraries, structure-activity relationship, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Pseudomonas aeruginosa; 詳細
• 細胞内の位置: Periplasm (Probable): Q9I194 Q9I194
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79966.64

構造登録者

Drake, E.J.,Wurst, J.M.,Theriault, J.R.,Munoz, B.,Gulick, A.M. (登録日: 2013-04-09, 公開日: 2014-06-18, 最終更新日: 2023-09-20)

• 主引用文献: Wurst, J.M.,Drake, E.J.,Theriault, J.R.,Jewett, I.T.,VerPlank, L.,Perez, J.R.,Dandapani, S.,Palmer, M.,Moskowitz, S.M.,Schreiber, S.L.,Munoz, B.,Gulick, A.M.; Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine.; Acs Chem.Biol., 9:1536-1544, 2014; PubMed: 24824984; DOI: 10.1021/cb5001586

実験手法

X-RAY DIFFRACTION (1.99 Å)