4K23
Structure of anti-uPAR Fab ATN-658
Summary for 4K23
Entry DOI | 10.2210/pdb4k23/pdb |
Related | 4K24 |
Descriptor | anti-uPAR antibody, heavy chain, anti-uPAR antibody, light chain (3 entities in total) |
Functional Keywords | immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 48639.39 |
Authors | |
Primary citation | Xu, X.,Cai, Y.,Wei, Y.,Donate, F.,Juarez, J.,Parry, G.,Chen, L.,Meehan, E.J.,Ahn, R.W.,Ugolkov, A.,Dubrovskyi, O.,O'halloran, T.V.,Huang, M.,Mazar, A.P. Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M) Plos One, 9:e85349-e85349, 2014 Cited by PubMed: 24465541DOI: 10.1371/journal.pone.0085349 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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