4JVN

Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and metabolite of brominated flame retardant 3OH BDE47 (3-hydroxyl bromodiphenyl ether)

Summary for 4JVN

Entry DOI	10.2210/pdb4jvn/pdb
Related	1G3M 4JVL 4JVM
Descriptor	Estrogen sulfotransferase, 2,6-dibromo-3-(2,4-dibromophenoxy)phenol, ADENOSINE-3'-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	sulfotransferase, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P49888
Total number of polymer chains	2
Total formula weight	72440.82
Authors	Gosavi, R.A.,Knudsen, G.A.,Birnbaum, L.S.,Pedersen, L.C. (deposition date: 2013-03-25, release date: 2013-09-04, Last modification date: 2023-09-20)
Primary citation	Gosavi, R.A.,Knudsen, G.A.,Birnbaum, L.S.,Pedersen, L.C. Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis. Environ.Health Perspect., 121:1194-1199, 2013 Cited by PubMed: 23959441 DOI: 10.1289/ehp.1306902 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation