4JVM
Crystal structure of human estrogen sulfotransferase (SULT1E1) in complex with inactive cofactor PAP and brominated flame retardant TBBPA (tetrabromobisphenol A)
Summary for 4JVM
Entry DOI | 10.2210/pdb4jvm/pdb |
Related | 1G3M 4JVL 4JVN |
Descriptor | Estrogen sulfotransferase, 4,4'-propane-2,2-diylbis(2,6-dibromophenol), ADENOSINE-3'-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | cytosolic sulfotransferase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P49888 |
Total number of polymer chains | 2 |
Total formula weight | 72672.10 |
Authors | Gosavi, R.A.,Knudsen, G.A.,Birnbaum, L.S.,Pedersen, L.C. (deposition date: 2013-03-25, release date: 2013-09-04, Last modification date: 2023-09-20) |
Primary citation | Gosavi, R.A.,Knudsen, G.A.,Birnbaum, L.S.,Pedersen, L.C. Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis. Environ.Health Perspect., 121:1194-1199, 2013 Cited by PubMed: 23959441DOI: 10.1289/ehp.1306902 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.994 Å) |
Structure validation
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