4JPI
Crystal structure of a putative VRC01 germline precursor Fab
Summary for 4JPI
Entry DOI | 10.2210/pdb4jpi/pdb |
Related | 4JPJ 4JPK |
Descriptor | Putative VRC01 germline Fab heavy chain, Putative VRC01 germline Fab light chain, GLYCEROL, ... (4 entities in total) |
Functional Keywords | anti-hiv-1, gp120, cd4 binding site-targeting, vrc01 broadly neutralizing antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 99646.74 |
Authors | Julien, J.-P.,Diwanji, D.C.,Jardine, J.,Schief, W.R.,Wilson, I.A. (deposition date: 2013-03-19, release date: 2013-04-10, Last modification date: 2023-09-20) |
Primary citation | Jardine, J.,Julien, J.P.,Menis, S.,Ota, T.,Kalyuzhniy, O.,McGuire, A.,Sok, D.,Huang, P.S.,MacPherson, S.,Jones, M.,Nieusma, T.,Mathison, J.,Baker, D.,Ward, A.B.,Burton, D.R.,Stamatatos, L.,Nemazee, D.,Wilson, I.A.,Schief, W.R. Rational HIV immunogen design to target specific germline B cell receptors. Science, 340:711-716, 2013 Cited by PubMed: 23539181DOI: 10.1126/science.1234150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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