4JMI

Sec7 domain of ARNO, an exchange factor, at 1.5 Angstrom resolution

Summary for 4JMI

Entry DOI	10.2210/pdb4jmi/pdb
Related	4JMO 4JWL 4JXH 4L5M
Descriptor	Cytohesin-2 (2 entities in total)
Functional Keywords	nucleotide exchange factors, arf1, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Peripheral membrane protein: Q99418
Total number of polymer chains	1
Total formula weight	23029.31
Authors	Hoh, F.,Rouhana, J. (deposition date: 2013-03-14, release date: 2013-10-23, Last modification date: 2023-11-08)
Primary citation	Rouhana, J.,Hoh, F.,Estaran, S.,Henriquet, C.,Boublik, Y.,Kerkour, A.,Trouillard, R.,Martinez, J.,Pugniere, M.,Padilla, A.,Chavanieu, A. Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors J.Med.Chem., 56:8497-8511, 2013 Cited by PubMed: 24112024 DOI: 10.1021/jm4009357 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation