4JHA

Crystal Structure of RSV-Neutralizing Human Antibody D25

Summary for 4JHA

• Entry DOI: 10.2210/pdb4jha/pdb
• Related: 4JHW
• Descriptor: D25 antigen-binding fragment heavy chain, D25 light chain (3 entities in total)
• Functional Keywords: immunoglobulin, ig, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47830.49

Authors

Mclellan, J.S.,Chen, M.,Leung, S.,Graepel, K.W.,Du, X.,Yang, Y.,Zhou, T.,Baxa, U.,Yasuda, E.,Beaumont, T.,Kumar, A.,Modjarrad, K.,Zheng, Z.,Zhao, M.,Xia, N.,Kwong, P.D.,Graham, B.S. (deposition date: 2013-03-04, release date: 2013-05-01, Last modification date: 2023-09-20)

• Primary citation: McLellan, J.S.,Chen, M.,Leung, S.,Graepel, K.W.,Du, X.,Yang, Y.,Zhou, T.,Baxa, U.,Yasuda, E.,Beaumont, T.,Kumar, A.,Modjarrad, K.,Zheng, Z.,Zhao, M.,Xia, N.,Kwong, P.D.,Graham, B.S.; Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.; Science, 340:1113-1117, 2013; PubMed: 23618766; DOI: 10.1126/science.1234914

Experimental method

X-RAY DIFFRACTION (1.6 Å)