4JEK

Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis

4JEK の概要

• エントリーDOI: 10.2210/pdb4jek/pdb
• 分子名称: Dibenzothiophene desulfurization enzyme C (2 entities in total)
• 機能のキーワード: dibenzothiophene desulfurization enzyme c, oxidoreductase
• 由来する生物種: Rhodococcus sp.
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 391232.94

構造登録者

Zhang, L.,Duan, X.L.,Zhou, D.M.,Li, X. (登録日: 2013-02-27, 公開日: 2013-09-18, 最終更新日: 2024-03-20)

主引用文献

Duan, X.,Zhang, L.,Zhou, D.,Ji, K.,Ma, T.,Shui, W.,Li, G.,Li, X.
Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Acta Crystallogr.,Sect.F, 69:597-601, 2013

PubMed Abstract: Dibenzothiophene (DBT) and its derivatives are typical sulfur compounds found in fossil fuels. These compounds show resistance to the hydrodesulfurization treatment that is commonly used in industry. Dibenzothiophene monooxygenase (DszC) is responsible for the oxidation of DBT, which is the first and the rate-limiting step in the DBT enzymatic desulfurization 4S pathway. In this study, the crystal structure of DszC from Rhodococcus erythropolis DS-3 is reported. The crystal of native DszC belonged to space group P1, with unit-cell parameters a = 96.16, b = 96.27, c = 98.56 Å, α = 81.03, β = 67.57, γ = 85.84°. To determine the phase, SAD X-ray diffraction data were collected from a SeMet-derivative DszC crystal, which also belonged to space group P1, with unit-cell parameters a = 95.379, b = 95.167, c = 94.891 Å, α = 87.046, β = 70.536, γ = 79.738°. Further structural analysis of DszC is in progress.

PubMed: 23722833
DOI: 10.1107/S1744309113011172

実験手法

X-RAY DIFFRACTION (2.4 Å)