4JC5

Immune activator bound to receptor

Summary for 4JC5

Entry DOI	10.2210/pdb4jc5/pdb
Descriptor	Transmembrane protein 173, (9-oxoacridin-10(9H)-yl)acetic acid (3 entities in total)
Functional Keywords	innate immune receptor, immune system
Biological source	Mus musculus (mouse)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : Q3TBT3
Total number of polymer chains	2
Total formula weight	46320.69
Authors	Deimling, T.,Hopfner, K.P. (deposition date: 2013-02-21, release date: 2013-05-08, Last modification date: 2024-02-28)
Primary citation	Cavlar, T.,Deimling, T.,Ablasser, A.,Hopfner, K.P.,Hornung, V. Species-specific detection of the antiviral small-molecule compound CMA by STING. Embo J., 32:1440-1450, 2013 Cited by PubMed: 23604073 DOI: 10.1038/emboj.2013.86 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation