Molecular basis for abrogation of activation of pro-inflammatory cytokines

Summary for 4JBK

Related4JBJ 4JBM
DescriptorInterferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3') (2 entities in total)
Functional Keywordsob fold, dna, dna binding protein-dna complex, dna binding protein/dna
Biological sourceMus musculus (mouse)
Cellular locationCytoplasm Q9R002
Total number of polymer chains8
Total molecular weight107935.9
Ru, H.,Ni, X.,Crowley, C.,Zhao, L.,Ding, W.,Hung, L.-W.,Shaw, N.,Cheng, G.,Liu, Z.-J. (deposition date: 2013-02-19, release date: 2013-06-26)
Primary citation
Ru, H.,Ni, X.,Zhao, L.,Crowley, C.,Ding, W.,Hung, L.-W.,Shaw, N.,Cheng, G.,Liu, Z.-J.
Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23:855-858, 2013
PubMed: 23567559 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2013.52
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.255100.3%3.8%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report