4JB6

Structure of Pseudomonas aeruginosa FabF mutant C164Q

Summary for 4JB6

• Entry DOI: 10.2210/pdb4jb6/pdb
• Related: 4b7v
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, POTASSIUM ION (3 entities in total)
• Functional Keywords: fatty acid biosynthesis, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 87216.20

Authors

Baum, B.,Lecker, L. (deposition date: 2013-02-19, release date: 2014-03-05, Last modification date: 2023-09-20)

• Primary citation: Baum, B.,Lecker, L.S.,Zoltner, M.,Jaenicke, E.,Schnell, R.,Hunter, W.N.,Brenk, R.; Structures of Pseudomonas aeruginosa beta-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form.; Acta Crystallogr F Struct Biol Commun, 71:1020-1026, 2015; PubMed: 26249693; DOI: 10.1107/S2053230X15010614

Experimental method

X-RAY DIFFRACTION (2.4 Å)