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4JB6

Structure of Pseudomonas aeruginosa FabF mutant C164Q

Summary for 4JB6
Entry DOI10.2210/pdb4jb6/pdb
Related4b7v
Descriptor3-oxoacyl-[acyl-carrier-protein] synthase 2, POTASSIUM ION (3 entities in total)
Functional Keywordsfatty acid biosynthesis, transferase
Biological sourcePseudomonas aeruginosa
Total number of polymer chains2
Total formula weight87216.20
Authors
Baum, B.,Lecker, L. (deposition date: 2013-02-19, release date: 2014-03-05, Last modification date: 2023-09-20)
Primary citationBaum, B.,Lecker, L.S.,Zoltner, M.,Jaenicke, E.,Schnell, R.,Hunter, W.N.,Brenk, R.
Structures of Pseudomonas aeruginosa beta-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form.
Acta Crystallogr F Struct Biol Commun, 71:1020-1026, 2015
Cited by
PubMed: 26249693
DOI: 10.1107/S2053230X15010614
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

221051

건을2024-06-12부터공개중

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