4JAZ
Crystal structure of the complex between PPARgamma LBD and trans-resveratrol
Summary for 4JAZ
Entry DOI | 10.2210/pdb4jaz/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, RESVERATROL (3 entities in total) |
Functional Keywords | bundle of alpha-helices, small four-strnded beta-sheet, activator, diabetes mellitus, disease mutation, dna-binding, nucleus, obesity, phosphorylation, receptor, transcription, transcription regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 65615.89 |
Authors | Pochetti, G.,Capelli, D.,Montanari, R.,Calleri, E.,Moaddel, R.,Temporini, C. (deposition date: 2013-02-19, release date: 2014-02-12, Last modification date: 2024-02-28) |
Primary citation | Calleri, E.,Pochetti, G.,Dossou, K.S.,Laghezza, A.,Montanari, R.,Capelli, D.,Prada, E.,Loiodice, F.,Massolini, G.,Bernier, M.,Moaddel, R. Resveratrol and Its Metabolites Bind to PPARs. Chembiochem, 15:1154-1160, 2014 Cited by PubMed: 24796862DOI: 10.1002/cbic.201300754 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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