4JAZ

Crystal structure of the complex between PPARgamma LBD and trans-resveratrol

4JAZ の概要

• エントリーDOI: 10.2210/pdb4jaz/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, RESVERATROL (3 entities in total)
• 機能のキーワード: bundle of alpha-helices, small four-strnded beta-sheet, activator, diabetes mellitus, disease mutation, dna-binding, nucleus, obesity, phosphorylation, receptor, transcription, transcription regulation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P37231
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65615.89

構造登録者

Pochetti, G.,Capelli, D.,Montanari, R.,Calleri, E.,Moaddel, R.,Temporini, C. (登録日: 2013-02-19, 公開日: 2014-02-12, 最終更新日: 2024-02-28)

• 主引用文献: Calleri, E.,Pochetti, G.,Dossou, K.S.,Laghezza, A.,Montanari, R.,Capelli, D.,Prada, E.,Loiodice, F.,Massolini, G.,Bernier, M.,Moaddel, R.; Resveratrol and Its Metabolites Bind to PPARs.; Chembiochem, 15:1154-1160, 2014; PubMed: 24796862; DOI: 10.1002/cbic.201300754

実験手法

X-RAY DIFFRACTION (2.85 Å)