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4J6B

The 2.2 A crystal structure of CYP154C5 from Nocardia farcinica in complex with pregnenolone

Summary for 4J6B
Entry DOI10.2210/pdb4j6b/pdb
Related4J6B 4J6C 4JBT
DescriptorCytochrome P450 monooxygenase, (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
Functional Keywordscytochrom p450, steroid hydroxylating monooxygenase, steroid binding, oxidoreductase-substrate complex, oxidoreductase/substrate
Biological sourceNocardia farcinica
Total number of polymer chains2
Total formula weight92891.36
Authors
Herzog, K.,Hoffmann, K.M. (deposition date: 2013-02-11, release date: 2014-03-05, Last modification date: 2023-09-20)
Primary citationHerzog, K.,Bracco, P.,Onoda, A.,Hayashi, T.,Hoffmann, K.,Schallmey, A.
Enzyme-substrate complex structures of CYP154C5 shed light on its mode of highly selective steroid hydroxylation.
Acta Crystallogr.,Sect.D, 70:2875-2889, 2014
Cited by
PubMed: 25372679
DOI: 10.1107/S1399004714019129
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

221051

건을2024-06-12부터공개중

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