4IZ9
Crystal structure of an acetate kinase from Mycobacterium avium bound to an unknown acid-ApCpp conjugate and manganese
Summary for 4IZ9
Entry DOI | 10.2210/pdb4iz9/pdb |
Related | 3p4i 3r9p 4dq8 4ijn |
Descriptor | Acetate kinase, MANGANESE (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total) |
Functional Keywords | structural genomics, seattle structural genomics center for infectious disease, ssgcid, acka, propionate kinase, acid-kinase, atp-dependent, non-hydrolyzable atp analog, anomalous manganese signal, unknown conjugate, transferase |
Biological source | Mycobacterium avium |
Cellular location | Cytoplasm : A0QLU8 |
Total number of polymer chains | 1 |
Total formula weight | 42577.56 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2013-01-29, release date: 2013-02-20, Last modification date: 2023-09-20) |
Primary citation | Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J. Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95:142-148, 2015 Cited by PubMed: 25613812DOI: 10.1016/j.tube.2014.12.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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