4IZ9

Crystal structure of an acetate kinase from Mycobacterium avium bound to an unknown acid-ApCpp conjugate and manganese

4IZ9 の概要

• エントリーDOI: 10.2210/pdb4iz9/pdb
• 関連するPDBエントリー: 3p4i 3r9p 4dq8 4ijn
• 分子名称: Acetate kinase, MANGANESE (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total)
• 機能のキーワード: structural genomics, seattle structural genomics center for infectious disease, ssgcid, acka, propionate kinase, acid-kinase, atp-dependent, non-hydrolyzable atp analog, anomalous manganese signal, unknown conjugate, transferase
• 由来する生物種: Mycobacterium avium
• 細胞内の位置: Cytoplasm : A0QLU8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42577.56

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2013-01-29, 公開日: 2013-02-20, 最終更新日: 2023-09-20)

• 主引用文献: Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.; Increasing the structural coverage of tuberculosis drug targets.; Tuberculosis (Edinb), 95:142-148, 2015; PubMed: 25613812; DOI: 10.1016/j.tube.2014.12.003

実験手法

X-RAY DIFFRACTION (1.98 Å)