4IY1

Structure of a 37-fold mutant of halohydrin dehalogenase (HheC) with chloride bound

4IY1 の概要

• エントリーDOI: 10.2210/pdb4iy1/pdb
• 関連するPDBエントリー: 4IXT 4IXW
• 分子名称: Halohydrin dehalogenase, CHLORIDE ION (3 entities in total)
• 機能のキーワード: thermostability, synergistic mutations, coupled mutations, proline-induced, backbone changes, enantioselectivity changes, directed evolution, protein engineering, short-chain dehydrogenase/reductase enzyme superfamily, cyanolysis, dehalogenase, atorvastatin synthesis, lyase
• 由来する生物種: Rhizobium radiobacter (Agrobacterium tumefaciens)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55789.17

構造登録者

Floor, R.J.,Schallmey, M.,Hauer, B.,Breuer, M.,Jekel, P.A.,Wijma, H.J.,Dijkstra, B.W.,Janssen, D.B. (登録日: 2013-01-28, 公開日: 2013-02-20, 最終更新日: 2023-09-20)

• 主引用文献: Schallmey, M.,Floor, R.J.,Hauer, B.,Breuer, M.,Jekel, P.A.,Wijma, H.J.,Dijkstra, B.W.,Janssen, D.B.; Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.; Chembiochem, 14:870-881, 2013; PubMed: 23585096; DOI: 10.1002/cbic.201300005

実験手法

X-RAY DIFFRACTION (2.1 Å)