4IUO

1.8 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) K170M Mutant in Complex with Quinate

4IUO の概要

• エントリーDOI: 10.2210/pdb4iuo/pdb
• 関連するPDBエントリー: 4GUI 4GUJ
• 分子名称: 3-dehydroquinate dehydratase, (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid (3 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, lyase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60590.98

構造登録者

Light, S.H.,Minasov, G.,Duban, M.-E.,Shuvalova, L.,Kwon, K.,Lavie, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2013-01-21, 公開日: 2013-01-30, 最終更新日: 2023-09-20)

• 主引用文献: Light, S.H.,Antanasijevic, A.,Krishna, S.N.,Caffrey, M.,Anderson, W.F.,Lavie, A.; Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of schiff base formation.; Biochemistry, 53:872-880, 2014; PubMed: 24437575; DOI: 10.1021/bi4015506

実験手法

X-RAY DIFFRACTION (1.8 Å)