4IPC

Structure of the N-terminal domain of RPA70, E7R mutant

Summary for 4IPC

Related4IPD 4IPG 4IPH
DescriptorReplication protein A 70 kDa DNA-binding subunit (2 entities in total)
Functional Keywordsob-fold, protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus P27694
Total number of polymer chains1
Total molecular weight13497.73
Authors
Feldkamp, M.D.,Frank, A.O.,Vangamudi, B.,Fesik, S.W.,Chazin, W.J. (deposition date: 2013-01-09, release date: 2013-09-11, Last modification date: 2013-10-02)
Primary citation
Feldkamp, M.D.,Frank, A.O.,Kennedy, J.P.,Patrone, J.D.,Vangamudi, B.,Waterson, A.G.,Fesik, S.W.,Chazin, W.J.
Surface Reengineering of RPA70N Enables Cocrystallization with an Inhibitor of the Replication Protein A Interaction Motif of ATR Interacting Protein.
Biochemistry, 52:6515-6524, 2013
PubMed: 23962067 (PDB entries with the same primary citation)
DOI: 10.1021/bi400542z
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.22 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.17770.8%1.9%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4ipc
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Molmil generated image of 4ipc
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Molmil generated image of 4ipc
rotated about y axis by 90°