4IO0

Crystal structure of F128A mutant of an epoxide hydrolase from Bacillus megaterium complexed with its product (R)-3-[1]naphthyloxy-propane-1,2-diol

Summary for 4IO0

Entry DOI	10.2210/pdb4io0/pdb
Related	4G00 4G02 4INZ
Descriptor	Soluble epoxide hydrolase, SULFATE ION, (2R)-3-(naphthalen-1-yloxy)propane-1,2-diol, ... (4 entities in total)
Functional Keywords	a/b hydrolase fold, epoxide hydrolase, hydrolase
Biological source	Bacillus megaterium
Total number of polymer chains	2
Total formula weight	71049.77
Authors	Kong, X.D.,Zhou, J.H.,Xu, J.H. (deposition date: 2013-01-07, release date: 2014-02-12, Last modification date: 2023-11-08)
Primary citation	Kong, X.D.,Yuan, S.,Li, L.,Chen, S.,Xu, J.H.,Zhou, J.H. Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates. Proc.Natl.Acad.Sci.USA, 111:15717-15722, 2014 Cited by PubMed: 25331869 DOI: 10.1073/pnas.1404915111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation