4IIQ

Crystal structure of a human MAIT TCR in complex with bovine MR1

4IIQ の概要

• エントリーDOI: 10.2210/pdb4iiq/pdb
• 分子名称: Human Mucosal Associated Invariant T cell receptor alpha chain, Human Mucosal Associated Invariant T cell receptor beta chain, Beta-2-microglobulin, MHC class I-related protein, ... (5 entities in total)
• 機能のキーワード: mhc-class i, immunoglobulin domain, immune system, antigen presentation, antigen recognition, cell membrane
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01888
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 96854.59

構造登録者

Lopez-Sagaseta, J.,Adams, E.J. (登録日: 2012-12-20, 公開日: 2013-04-24, 最終更新日: 2017-08-23)

• 主引用文献: Lopez-Sagaseta, J.,Dulberger, C.L.,Crooks, J.E.,Parks, C.D.,Luoma, A.M.,McFedries, A.,Van Rhijn, I.,Saghatelian, A.,Adams, E.J.; The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.; Proc.Natl.Acad.Sci.USA, 110:E1771-E1778, 2013; PubMed: 23613577; DOI: 10.1073/pnas.1222678110

実験手法

X-RAY DIFFRACTION (2.86 Å)