4IHP

Crystal structure of TgCDPK1 with inhibitor bound

Summary for 4IHP

• Entry DOI: 10.2210/pdb4ihp/pdb
• Descriptor: Calmodulin-domain protein kinase 1, 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 57650.81

Authors

El Bakkouri, M.,Tempel, W.,Crandall, I.E.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, C.K.,Shokat, K.M.,Sibley, L.D.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2012-12-19, release date: 2014-01-15, Last modification date: 2024-02-28)

• Primary citation: El Bakkouri, M.,Tempel, W.,Crandall, I.E.,Massad, T.,Loppnau, P.,Graslund, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Kain, C.K.,Shokat, K.M.,Sibley, L.D.,Hui, R.,Structural Genomics Consortium (SGC); Crystal structure of TgCDPK1 with inhibitor bound; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.27 Å)