4IFW

Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, ADP inhibited form

Summary for 4IFW

Entry DOI	10.2210/pdb4ifw/pdb
Descriptor	Thiamine biosynthesis lipoprotein ApbE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	hydrolase, bimetal center, fad pyrophosphatase, flavin turnover, treponema pallidum, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Treponema pallidum subsp. pallidum
Cellular location	Cell inner membrane ; Lipid-anchor ; Periplasmic side : O83774
Total number of polymer chains	1
Total formula weight	37218.79
Authors	Tomchick, D.R.,Brautigam, C.A.,Deka, R.K.,Norgard, M.V. (deposition date: 2012-12-15, release date: 2013-02-27, Last modification date: 2023-09-20)
Primary citation	Deka, R.K.,Brautigam, C.A.,Liu, W.Z.,Tomchick, D.R.,Norgard, M.V. The TP0796 Lipoprotein of Treponema pallidum Is a Bimetal-dependent FAD Pyrophosphatase with a Potential Role in Flavin Homeostasis. J.Biol.Chem., 288:11106-11121, 2013 Cited by PubMed: 23447540 DOI: 10.1074/jbc.M113.449975 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3001 Å)

Structure validation