4IER

Cys-persulfenate bound Cysteine Dioxygenase at pH 5.5 in the presence of Cys

4IER の概要

• エントリーDOI: 10.2210/pdb4ier/pdb
• 関連するPDBエントリー: 4IEO 4IEP 4IEQ 4IES 4IET 4IEU 4IEV 4IEW 4IEX 4IEY 4IEZ 4IF0 4IF1
• 分子名称: Cysteine dioxygenase type 1, FE (II) ION, S-HYDROPEROXYCYSTEINE, ... (4 entities in total)
• 機能のキーワード: cupin fold, catalyzes oxidation, cysteine to cysteine sulfinate, c93-y157 crosslink, cytosol, oxidoreductase
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23267.89

構造登録者

Driggers, C.M.,Cooley, R.B.,Karplus, P.A. (登録日: 2012-12-13, 公開日: 2013-06-26, 最終更新日: 2013-09-11)

• 主引用文献: Driggers, C.M.,Cooley, R.B.,Sankaran, B.,Hirschberger, L.L.,Stipanuk, M.H.,Karplus, P.A.; Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH.; J.Mol.Biol., 425:3121-3136, 2013; PubMed: 23747973; DOI: 10.1016/j.jmb.2013.05.028

実験手法

X-RAY DIFFRACTION (1.45 Å)