4I1S

Melanoma differentiation associated protein-5 Helicase domain complex with inhibitor Non-structural protein V

4I1S の概要

• エントリーDOI: 10.2210/pdb4i1s/pdb
• 分子名称: Melanoma differentiation associated protein-5, Non-structural protein V, ZINC ION, ... (4 entities in total)
• 機能のキーワード: sf2-atpase, helicase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Sus scrofa (pigs,swine,wild boar); 詳細
• 細胞内の位置: Host cytoplasm : P11207
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34562.13

構造登録者

Motz, C.,Witte, G.,Hopfner, K.P. (登録日: 2012-11-21, 公開日: 2013-01-30, 最終更新日: 2017-07-26)

• 主引用文献: Motz, C.,Schuhmann, K.M.,Kirchhofer, A.,Moldt, M.,Witte, G.,Conzelmann, K.K.,Hopfner, K.P.; Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.; Science, 339:690-693, 2013; PubMed: 23328395; DOI: 10.1126/science.1230949

実験手法

X-RAY DIFFRACTION (2.293 Å)