4HZO

The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold

4HZO の概要

• エントリーDOI: 10.2210/pdb4hzo/pdb
• 関連するPDBエントリー: 4HZN
• 分子名称: Bifunctional methylmalonyl-CoA:ACP acyltransferase/decarboxylase, CHLORIDE ION, COENZYME A, ... (4 entities in total)
• 機能のキーワード: structural genomics, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, psi-biology, double hot dog fold, acyl carrier protein - lnml, transferase, lyase
• 由来する生物種: Streptomyces atroolivaceus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36082.27

構造登録者

Lohman, J.R.,Bingman, C.A.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2012-11-15, 公開日: 2013-01-30, 最終更新日: 2024-02-28)

• 主引用文献: Lohman, J.R.,Bingman, C.A.,Phillips, G.N.,Shen, B.; Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.; Biochemistry, 52:902-911, 2013; PubMed: 23320975; DOI: 10.1021/bi301652y

実験手法

X-RAY DIFFRACTION (1.76 Å)