4HXY

PlmKR1-Ketoreductase from the first module of phoslactomycin biosynthesis in Streptomyces sp. HK803

4HXY の概要

• エントリーDOI: 10.2210/pdb4hxy/pdb
• 分子名称: Plm1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-AMINOHEXANOIC ACID, ... (4 entities in total)
• 機能のキーワード: short chain dehydrogenase/reductase, ketoreductase, rossmann fold, oxidoreductase
• 由来する生物種: Streptomyces sp. HK803
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92701.95

構造登録者

Whicher, J.R.,Smith, J.L. (登録日: 2012-11-12, 公開日: 2013-07-10, 最終更新日: 2023-11-15)

• 主引用文献: Bonnett, S.A.,Whicher, J.R.,Papireddy, K.,Florova, G.,Smith, J.L.,Reynolds, K.A.; Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene.; Chem.Biol., 20:772-783, 2013; PubMed: 23790488; DOI: 10.1016/j.chembiol.2013.04.014

実験手法

X-RAY DIFFRACTION (1.68 Å)