4HUT

Structure of ATP:co(I)rrinoid adenosyltransferase (CobA) from Salmonella enterica in complex with four and five-coordinate cob(II)alamin and ATP

4HUT の概要

• エントリーDOI: 10.2210/pdb4hut/pdb
• 関連するPDBエントリー: 1G5R 1G5T 1G64
• 分子名称: Cob(I)yrinic acid a,c-diamide adenosyltransferase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• 細胞内の位置: Cytoplasm: P31570
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46115.92

構造登録者

Moore, T.C.,Newmister, S.A.,Rayment, I.,Escalante-Semerena, J.C. (登録日: 2012-11-04, 公開日: 2013-01-23, 最終更新日: 2023-09-20)

• 主引用文献: Moore, T.C.,Newmister, S.A.,Rayment, I.,Escalante-Semerena, J.C.; Structural Insights into the Mechanism of Four-Coordinate Cob(II)alamin Formation in the Active Site of the Salmonella enterica ATP:Co(I)rrinoid Adenosyltransferase Enzyme: Critical Role of Residues Phe91 and Trp93.; Biochemistry, 51:9647-9657, 2012; PubMed: 23148601; DOI: 10.1021/bi301378d

実験手法

X-RAY DIFFRACTION (1.95 Å)