4HQZ

Crystal structure of the pneumoccocal exposed lipoprotein thioredoxin sp_1000 (Etrx2) from Streptococcus pneumoniae strain TIGR4 in complex with 2-hydroxyethyl disulfide

Summary for 4HQZ

• Entry DOI: 10.2210/pdb4hqz/pdb
• Related: 4HQS
• Descriptor: Thioredoxin family protein, 2-HYDROXYETHYL DISULFIDE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: lipoprotein, disulfide bridge, thiorredoxin, membrane, oxidoreductase
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 42540.15

Authors

Bartual, S.G.,Saleh, M.,Abdullah, M.R.,Jensch, I.,Asmat, T.M.,Petruschka, L.,Pribyl, T.,Hermoso, J.A.,Hammerschmidt, S. (deposition date: 2012-10-26, release date: 2013-12-25, Last modification date: 2023-11-08)

• Primary citation: Saleh, M.,Bartual, S.G.,Abdullah, M.R.,Jensch, I.,Asmat, T.M.,Petruschka, L.,Pribyl, T.,Gellert, M.,Lillig, C.H.,Antelmann, H.,Hermoso, J.A.,Hammerschmidt, S.; Molecular architecture of Streptococcus pneumoniae surface thioredoxin-fold lipoproteins crucial for extracellular oxidative stress resistance and maintenance of virulence.; EMBO Mol Med, 5:1852-1870, 2013; PubMed: 24136784; DOI: 10.1002/emmm.201202435

Experimental method

X-RAY DIFFRACTION (1.22 Å)