4HLQ

Crystal structure of human rab1b bound to GDP and BEF3 in complex with the GAP domain of TBC1D20 from homo sapiens

4HLQ の概要

• エントリーDOI: 10.2210/pdb4hlq/pdb
• 関連するPDBエントリー: 4HL4
• 分子名称: TBC1 domain family member 20, Ras-related protein Rab-1B, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: rab1b, rabgap, fluorides, gtpase-activating proteins, rab gtp-binding proteins, hydrolase activator-protein transport complex, hydrolase activator/protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein (Potential): Q96BZ9; Membrane; Lipid-anchor; Cytoplasmic side: Q9H0U4
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 276725.29

構造登録者

Gazdag, E.M.,Gavriljuk, K.,Itzen, A.,Koetting, C.,Gerwert, K.,Goody, R.S. (登録日: 2012-10-17, 公開日: 2013-01-16, 最終更新日: 2023-11-08)

• 主引用文献: Gavriljuk, K.,Gazdag, E.M.,Itzen, A.,Kotting, C.,Goody, R.S.,Gerwert, K.; Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail.; Proc.Natl.Acad.Sci.USA, 109:21348-21353, 2012; PubMed: 23236136; DOI: 10.1073/pnas.1214431110

実験手法

X-RAY DIFFRACTION (3.3 Å)