4HK7

Crystal structure of Cordyceps militaris IDCase in complex with uracil

Summary for 4HK7

Entry DOI	10.2210/pdb4hk7/pdb
Related	4HJW 4HK5 4HK6
Descriptor	Uracil-5-carboxylate decarboxylase, ZINC ION, URACIL, ... (4 entities in total)
Functional Keywords	pyrimidine metabolism, dna decarboxylation, idcase, decarboxylase, uracil, lyase
Biological source	Cordyceps militaris (Caterpillar fungus)
Total number of polymer chains	4
Total formula weight	169110.44
Authors	Xu, S.,Zhu, J.,Ding, J. (deposition date: 2012-10-15, release date: 2013-09-11, Last modification date: 2023-09-20)
Primary citation	Xu, S.,Li, W.,Zhu, J.,Wang, R.,Li, Z.,Xu, G.L.,Ding, J. Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23:1296-1309, 2013 Cited by PubMed: 23917530 DOI: 10.1038/cr.2013.107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.189 Å)

Structure validation