4HIV
Structure of actinomycin D d(ATGCGGCAT) complex
Summary for 4HIV
Entry DOI | 10.2210/pdb4hiv/pdb |
Related PRD ID | PRD_000001 |
Descriptor | DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*AP*T)-3'), ACTINOMYCIN D (3 entities in total) |
Functional Keywords | double helix dna, nucleotide flipping-out, sharp kink, left-handed twist, cgg tripleat repeat, neurological disease, dna-antibiotic complex, dna/antibiotic |
Biological source | Streptomyces antibioticus |
Total number of polymer chains | 4 |
Total formula weight | 8094.54 |
Authors | Lo, Y.S.,Tseng, W.H.,Hou, M.H. (deposition date: 2012-10-12, release date: 2013-05-08, Last modification date: 2024-07-10) |
Primary citation | Lo, Y.S.,Tseng, W.H.,Chuang, C.Y.,Hou, M.H. The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats. Nucleic Acids Res., 41:4284-4294, 2013 Cited by PubMed: 23408860DOI: 10.1093/nar/gkt084 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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