4GYI

Crystal structure of the Rio2 kinase-ADP/Mg2+-phosphoaspartate complex from Chaetomium thermophilum

Summary for 4GYI

• Entry DOI: 10.2210/pdb4gyi/pdb
• Related: 4GYG
• Descriptor: Rio2 kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: protein kinase, adp complex, phosphoaspartate, acyl-phosphate, ribosome biogenesis, ser/thr protein kinase, ribosome biogenesis; ribosomal rna processing; pre-40s maturation, pre-40s, phosphorylation, transferase
• Biological source: Chaetomium thermophilum
• Total number of polymer chains: 1
• Total formula weight: 45347.47

Authors

Ferreira-Cerca, S.,Sagar, V.,Schafer, T.,Diop, M.,Wesseling, A.M.,Lu, H.,Chai, E.,Hurt, E.,LaRonde-LeBlanc, N. (deposition date: 2012-09-05, release date: 2012-10-17, Last modification date: 2023-09-13)

• Primary citation: Ferreira-Cerca, S.,Sagar, V.,Schafer, T.,Diop, M.,Wesseling, A.M.,Lu, H.,Chai, E.,Hurt, E.,Laronde-Leblanc, N.; ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit.; Nat.Struct.Mol.Biol., 19:1316-1323, 2012; PubMed: 23104056; DOI: 10.1038/nsmb.2403

Experimental method

X-RAY DIFFRACTION (2.2 Å)