4GWI

His 62 mutant of the lectin binding domain of lectinolysin complexed with Lewis y

Summary for 4GWI

• Entry DOI: 10.2210/pdb4gwi/pdb
• Related: 3GWJ 3LEG 3LEI 3LEK 3LEO
• Related PRD ID: PRD_900054
• Descriptor: Platelet aggregation factor Sm-hPAF, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: cholesterol-dependent cytolysins, lewis antigens, f-type lectin fold, glycan binding, sugar binding protein
• Biological source: Streptococcus mitis
• Cellular location: Secreted : Q2PHL4
• Total number of polymer chains: 1
• Total formula weight: 17698.87

Authors

Feil, S.C. (deposition date: 2012-09-03, release date: 2012-11-21, Last modification date: 2024-03-20)

• Primary citation: Lawrence, S.L.,Feil, S.C.,Holien, J.K.,Kuiper, M.J.,Doughty, L.,Dolezal, O.,Mulhern, T.D.,Tweten, R.K.,Parker, M.W.; Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin; Front Immunol, 3:330-330, 2012; PubMed: 23181061; DOI: 10.3389/fimmu.2012.00330

Experimental method

X-RAY DIFFRACTION (1.6 Å)