4GW5
cQYN meditope - Cetuximab Fab
Summary for 4GW5
Entry DOI | 10.2210/pdb4gw5/pdb |
Related | 4gw1 |
Descriptor | Fab Light Chain, Fab Heavy Chain, cQYN meditope, ... (5 entities in total) |
Functional Keywords | igg, immune system, egfr |
Biological source | Mus musculus,Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 97408.95 |
Authors | Donaldson, J.M.,Zer, C.,Avery, K.N.,Bzymek, K.P.,Horne, D.A.,Williams, J.C. (deposition date: 2012-08-31, release date: 2013-10-09, Last modification date: 2023-09-13) |
Primary citation | Donaldson, J.M.,Zer, C.,Avery, K.N.,Bzymek, K.P.,Horne, D.A.,Williams, J.C. Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 110:17456-17461, 2013 Cited by PubMed: 24101516DOI: 10.1073/pnas.1307309110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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