4GUP

Structure of MHC-class I related molecule MR1

4GUP の概要

• エントリーDOI: 10.2210/pdb4gup/pdb
• 分子名称: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, ... (5 entities in total)
• 機能のキーワード: mhc class i-related protein, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted: Q95460; Secreted: P61769
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 87432.38

構造登録者

Patel, O.,Le Nours, J.,Rossjohn, J. (登録日: 2012-08-29, 公開日: 2012-10-17, 最終更新日: 2023-11-08)

• 主引用文献: Kjer-Nielsen, L.,Patel, O.,Corbett, A.J.,Le Nours, J.,Meehan, B.,Liu, L.,Bhati, M.,Chen, Z.,Kostenko, L.,Reantragoon, R.,Williamson, N.A.,Purcell, A.W.,Dudek, N.L.,McConville, M.J.,O'Hair, R.A.J.,Khairallah, G.N.,Godfrey, D.I.,Fairlie, D.P.,Rossjohn, J.,McCluskey, J.; MR1 presents microbial vitamin B metabolites to MAIT cells; Nature, 491:717-723, 2012; PubMed: 23051753; DOI: 10.1038/nature11605

実験手法

X-RAY DIFFRACTION (3.2 Å)