4GRD

Crystal structure of Phosphoribosylaminoimidazole carboxylase catalytic subunit from Burkholderia cenocepacia J2315

4GRD の概要

• エントリーDOI: 10.2210/pdb4grd/pdb
• 分子名称: Phosphoribosylaminoimidazole carboxylase catalytic subunit (2 entities in total)
• 機能のキーワード: ssgcid, nih, niaid, sbri, uw, emerald biostructures, phosphoribosylaminoimidazole carboxylase, purine nucleotides de novo biosynthesis, structural genomics, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, lyase, isomerase
• 由来する生物種: Burkholderia cenocepacia
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 72591.80

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-08-24, 公開日: 2012-09-12, 最終更新日: 2024-05-29)

• 主引用文献: Belfon, K.K.J.,Sharma, N.,Zigweid, R.,Bolejack, M.,Davies, D.,Edwards, T.E.,Myler, P.J.,French, J.B.; Structure-Guided Discovery of N 5 -CAIR Mutase Inhibitors.; Biochemistry, 62:2587-2596, 2023; PubMed: 37552766; DOI: 10.1021/acs.biochem.2c00705

実験手法

X-RAY DIFFRACTION (1.85 Å)