Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38

Summary for 4GOE

Related4GOC 4GOD 4GOF
DescriptorSmall glutamine-rich tetratricopeptide repeat-containing protein alpha, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsfour-helix bundle, protein-protein interaction, ubl4a ubiquitin-like domain, protein binding
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight11590.6
Chartron, J.W.,VanderVelde, D.G.,Clemons Jr., W.M. (deposition date: 2012-08-19, release date: 2012-11-21, Last modification date: 2013-01-16)
Primary citation
Chartron, J.W.,Vandervelde, D.G.,Clemons, W.M.
Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2:1620-1632, 2012
PubMed: 23142665 (PDB entries with the same primary citation)
DOI: 10.1016/j.celrep.2012.10.010
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.205101.2%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution