4GLP
The crystal structure of soluble human CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket.
Summary for 4GLP
Entry DOI | 10.2210/pdb4glp/pdb |
Descriptor | Monocyte differentiation antigen CD14 (1 entity in total) |
Functional Keywords | alpha beta bent solenoid, lrr, lipopolysaccharide, serum, cd14, leucine-rich repeat, pattern recognition, endotoxin, sepsis, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane ; Lipid- anchor, GPI-anchor : P08571 |
Total number of polymer chains | 1 |
Total formula weight | 33509.28 |
Authors | Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I. (deposition date: 2012-08-14, release date: 2012-12-26, Last modification date: 2021-05-26) |
Primary citation | Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I. The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket. J.Immunol., 190:1304-1311, 2013 Cited by PubMed: 23264655DOI: 10.4049/jimmunol.1202446 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.002 Å) |
Structure validation
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