4GLP

The crystal structure of soluble human CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket.

4GLP の概要

• エントリーDOI: 10.2210/pdb4glp/pdb
• 分子名称: Monocyte differentiation antigen CD14 (1 entity in total)
• 機能のキーワード: alpha beta bent solenoid, lrr, lipopolysaccharide, serum, cd14, leucine-rich repeat, pattern recognition, endotoxin, sepsis, immune system
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Lipid- anchor, GPI-anchor : P08571
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33509.28

構造登録者

Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I. (登録日: 2012-08-14, 公開日: 2012-12-26, 最終更新日: 2021-05-26)

• 主引用文献: Kelley, S.L.,Lukk, T.,Nair, S.K.,Tapping, R.I.; The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket.; J.Immunol., 190:1304-1311, 2013; PubMed: 23264655; DOI: 10.4049/jimmunol.1202446

実験手法

X-RAY DIFFRACTION (4.002 Å)