Crystal structure of TRAF3/Cardif

Summary for 4GHU

DescriptorTNF receptor-associated factor 3, Mitochondrial antiviral-signaling protein (3 entities in total)
Functional Keywordsalpha/beta, innate immunity, ifn pathway, immune system
Biological sourceMus musculus (mouse)
Cellular locationCytoplasm Q60803
Mitochondrion outer membrane (By similarity) Q8VCF0
Total number of polymer chains2
Total molecular weight24928.43
Zhang, P. (deposition date: 2012-08-08, release date: 2012-11-28)
Primary citation
Zhang, P.,Reichardt, A.,Liang, H.,Aliyari, R.,Cheng, D.,Wang, Y.,Xu, F.,Cheng, G.,Liu, Y.
Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5:ra81-ra81, 2012
PubMed: 23150880 (PDB entries with the same primary citation)
DOI: 10.1126/scisignal.2003152
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22090.5%3.3%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution