4GAY

Structure of the broadly neutralizing antibody AP33

Summary for 4GAY

• Entry DOI: 10.2210/pdb4gay/pdb
• Related: 4GAG 4GAJ
• Descriptor: NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, TRIETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: antibody fab, neutralizing antibody, hcv e2, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 4
• Total formula weight: 95497.89

Authors

Potter, J.A.,Owsianka, A.,Jeffery, N.,Matthews, D.,Keck, Z.,Lau, P.,Foung, S.K.H.,Taylor, G.L.,Patel, A.H. (deposition date: 2012-07-26, release date: 2012-10-10, Last modification date: 2012-11-21)

• Primary citation: Potter, J.A.,Owsianka, A.M.,Jeffery, N.,Matthews, D.J.,Keck, Z.Y.,Lau, P.,Foung, S.K.,Taylor, G.L.,Patel, A.H.; Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.; J.Virol., 86:12923-12932, 2012; PubMed: 22993159; DOI: 10.1128/JVI.02052-12

Experimental method

X-RAY DIFFRACTION (2.65 Å)