4GAJ
Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 411-424)
Summary for 4GAJ
| Entry DOI | 10.2210/pdb4gaj/pdb |
| Related | 4GAG 4GAY |
| Descriptor | NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, Genome polyprotein, ... (4 entities in total) |
| Functional Keywords | antibody fab, neutralizing antibody, hcv e2 binding, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 3 |
| Total formula weight | 49266.64 |
| Authors | Potter, J.A.,Owsianka, A.,Taylor, G.L.,Patel, A.H. (deposition date: 2012-07-25, release date: 2012-10-10, Last modification date: 2018-01-24) |
| Primary citation | Potter, J.A.,Owsianka, A.M.,Jeffery, N.,Matthews, D.J.,Keck, Z.Y.,Lau, P.,Foung, S.K.,Taylor, G.L.,Patel, A.H. Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody. J.Virol., 86:12923-12932, 2012 Cited by PubMed: 22993159DOI: 10.1128/JVI.02052-12 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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